Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was generated against a protein secreted by the T47D (clone 11) human breast carcinoma cell line.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
CU-18 detects a human breast carcinoma associated glycoprotein BCA-225, a 225 kD glycoprotein secreted by the T47D breast carcinoma cell line.
- Application References
(PubMed link indicates BioLegend citation) - RRID
- AB_2616963 (BioLegend Cat. No. 915004)
Antigen Details
- Structure
- BRST-1 is a 35 kD protein.
- Distribution
-
Cytoplasm, extracellular, and nucleus.
- Function
- BRST-1 may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. BRST-1 plays a role in embryonic stem cells proliferation and differentiation.
- Biology Area
- Cell Adhesion, Cell Biology
- Gene ID
- 4072 View all products for this Gene ID
- UniProt
- View information about BRST-1 on UniProt.org
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