Product Details
- Verified Reactivity
- Human
- Reported Reactivity
- Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- RRID
- AB_2904431 (BioLegend Cat. No. 519505) AB_2904431 (BioLegend Cat. No. 519506)
Antigen Details
- Structure
- CXC chemokine family, 8.7 kD
- Distribution
-
Monocytes, endothelial cells, and fibroblasts
- Function
- Interacts with CXCR3 and serves as a chemoattractant for T cells, dendritic cells, monocytes/macrophages, and NK cells
- Ligand/Receptor
- CXCR3
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Fibroblasts, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Luster AD, et al. 1987. Proc. Natl. Acad. Sci. USA 84:2868.
2. Kaplan G, et al. 1987. J. Exp. Med. 166:1098.
3. Sarris AH, et al. 1993. J. Exp. Med. 178:1127. - Gene ID
- 3627 View all products for this Gene ID
- UniProt
- View information about CXCL10 on UniProt.org
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