Product Details
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human HOMER1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 0.5??g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This product is not recommended for use in Immunohistochemistry.
This product does not recognize mouse or human HOMER1 in Western Blot.
This product only recognizes full length HOMER1 (Homer1b/c) and not the truncated variant Homer1a.
Antigen Details
- Structure
- HOMER1 is a 354 amino acid protein with a predicted molecular weight of 40 kD.
- Distribution
-
Post-synaptic density
- Function
- Protein-protein interactions, synaptic plasticity
- Interaction
- Homodimer; also interacts with other major components of the PSD including Shank family proteins, cytoskeletal proteins like dynamin, and receptors such as group 1 metabotropic glutamate receptors and the ryanodine receptor.
- Cell Type
- Mature Neurons, Neurons
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Signal Transduction, Synaptic Biology
- Molecular Family
- Postsynaptic proteins, Scaffold Proteins
- Antigen References
-
- Foa L, et al. 2001. Nat Neurosci. 4:499-506.
- de Bartolomeis A, et al. 2022. Neurosci Biobehav Rev. 136:104596.
- Salanova M, et al. 2013. IUBMB Life. 65:769-76.
- Reshetnikov VV, et al. 2021. Biochemistry (Mosc). 86:613-626.
- Gene ID
- 9456 View all products for this Gene ID
- UniProt
- View information about HOMER1 on UniProt.org
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