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Brilliant Violet 421™ anti-mouse CD193 (CCR3

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Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CCR3-transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.


Learn more about Brilliant Violet?.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Excitation Laser
Violet Laser (405 nm)
Product Citations
  1. Knuplez E, et al. 2021. British Journal of Pharmacology. 178(5):1234-1248. PubMed
RRID
AB_2565743 (BioLegend Cat. No. 144517)

Antigen Details

Structure
G-protein coupled, seven transmembrane domain receptor, 356 amino acids
Distribution

Eosinophils, basophils, mast, mononuclear phagocytes, platelets, hematopoietic progenitor, keratinocytes

Function
Co-receptor for HIV-1 and HIV-2, allergy
Ligand/Receptor
Eotaxin, eotaxin-2, eotaxin-3, RANTES, MCP-3, and MCP-4
Cell Type
Basophils, Eosinophils, Hematopoietic stem and progenitors, Mast cells, Platelets
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Zlotnik A, et al. 2006. Genome Biol. 7:243.
2. Kodali RB, et al. 2004. Arterioscler. Thromb. Vasc. Biol. 24:1211.
3. Das AM, et al. 2006. J. Pharmacol. Exp. Ther. 318:411.
4. Huaux F, et al. 2005. Am. J. Pathol. 167:1485.
5. Puxeddu I, et al. 2006. J. Allergy Clin. Immunol. 117:103.

Gene ID
12771 View all products for this Gene ID
UniProt
View information about CD193 on UniProt.org
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