Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human FGF-basic.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ELISA Capture - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration of 2 ?g/ml of the capture antibody was utilized to generate the example standard curve. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
ELISA Capture: The purified BHFB15 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated JKFb-2 antibody as the detecting antibody.
- RRID
- AB_2561316 (BioLegend Cat. No. 514801) AB_2561317 (BioLegend Cat. No. 514802)
Antigen Details
- Structure
- 17.2 kD (Mammalian)
- Distribution
-
Brain, retina, pituitary, kidney, placenta, testis, corpus luteum, adrenal glands, monocytes, prostate, bone, liver, cartiliage, endothelial cells, and epithelial cells.
- Function
- Released after tissue injuries and during the inflammatory process.
- Interaction
- Fibroblasts, myobalasts, osteoblasts, neuronal cells, endothelial cells, kerintocytes, chrondrocytes, astrocytes, oligodendrocytes, and the smooth muscle.
- Ligand/Receptor
- FGFR1-1 (flg); FGFR-2 (bek, K-sam); FGFR-4 (flig-2); low affinity coreceptor heparin sulfate, and heparin sulfate proteoglycans required for full activity.
- Cell Type
- Monocytes, Epithelial cells, Endothelial cells
- Biology Area
- Angiogenesis, Cell Biology, Immunology, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules, Cytokines/Chemokines, Growth Factors
- Antigen References
-
1. Fitzgerald KA, et al. 2013. The Cytokine Factsbook. Acadmic Press. San Diego.
2. Klagsbrun M, 1992. Semin. Cancer Biol. 3:81.
3. Goldfarb M. 1990. Cell Growth Factor. 1:439.
4. Sensenbrenner M. 1993. Prog. Neurobiol. 6:683. - Gene ID
- 2247 View all products for this Gene ID
- UniProt
- View information about FGF-basic on UniProt.org
