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Biotin anti-human CD198 (CCR8) Antibody

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Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CCR8-transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2629656 (BioLegend Cat. No. 360606)

Antigen Details

Structure
Seven hydrophobic transmembrane domains
Distribution

Vascular smooth muscle cells, macrophages, eosinophils, peritoneal macrophages, thymocytes, T cells, Langerhans cells and neurons

Function
Regulation of monocyte chemotaxis and thymic cell apoptosis
Ligand/Receptor
CCL1, CCL18
Cell Type
Dendritic cells, Eosinophils, Langerhans cells, Macrophages, Neurons, T cells, Thymocytes
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Tiffany HL, et al. 1997. J. Exp. Med. 186:165.
2. Goya I, et al. 1998. J. Immunol. 160:1975.
3. Lee S, et al. 2000. J. Virol. 74:6946.
4. Chensue SW, et al. 2001. J. Exp. Med. 193:573.
5. Qu C, et al. 2004. J. Exp. Med. 200:1231.
6. Isolam SA, et al. 2003. J. Exp. Med. 210:1889.

Gene ID
1237 View all products for this Gene ID
UniProt
View information about CD198 on UniProt.org
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