Product Details
- Verified Reactivity
- Human
- Reported Reactivity
- Pigtailed Macaque
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) - Product Citations
-
- RRID
- AB_10643416 (BioLegend Cat. No. 349301)
Antigen Details
- Structure
- Immunoglobulin superfamily, associates with TCR Vα chain and CD3 complex
- Distribution
-
Subset of TCR αβ+ T cells
- Function
- Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune response
- Ligand/Receptor
- MHC-peptide complex
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
-
1. Kuchroo VK, et al. 2002. Annu. Rev. Immunol. 20:101.
2. Venturi V, et al. 2008. Nat. Rev. Immunol. 8:231.
3. Matsumoto Y, et al. 2003. J. Immunol. 170:4846.
4. Killestein J, et al. 2002. Ann. Neurol. 51:467. - Gene ID
- 6957 View all products for this Gene ID
- UniProt
- View information about TCR V beta5 on UniProt.org
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