Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: in vitro blocking of antigen-induced proliferation of Vβ13+ T cells 1 and in vivo depletion of Vβ13+ T cells1.
- Application References
(PubMed link indicates BioLegend citation) -
- Zaller DM, et al. 1990. J. Exp. Med. 171:1943. (Block)
- Product Citations
-
- RRID
- AB_10645512 (BioLegend Cat. No. 140703) AB_10639945 (BioLegend Cat. No. 140704)
Antigen Details
- Structure
- Member of the immunoglobulin superfamily, Vβ13 is a variant of the TCR β chain which associates with the TCR α chain to form the TCR heterodimer.
- Distribution
- Expressed on a subset of TCR αβ+ T cells.
- Function
- Recognition of peptides presented by the MHC molecules, responsible for T cell mediated immune responses.
- Ligand/Receptor
- MHC-Peptide complex
- Cell Type
- T cells
- Biology Area
- Immunology, Adaptive Immunity
- Molecular Family
- TCRs
- Antigen References
-
1. Zaller DM, et al. 1990. J. Exp. Med. 171:1943.
2. Gentile F, et al. 2004. Immunology 112:13.
3. Lode HN, et al. 1999. P. Natl. Acad. Sci. USA 96:8591. - Gene ID
- 21577 View all products for this Gene ID
- UniProt
- View information about TCR V beta13 on UniProt.org
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