| 產(chǎn)品編號(hào) | bs-0884P |
| 英文名稱 | Recombinant human IL-1Ra protein, His |
| 中文名稱 | 重組人白介素-1受體拮抗劑蛋白 |
| 別 名 | Recombinant Human Interleukin-1 receptor antagonist His Tag; Recombinant human IL-1Ra protein, His |
| 理論分子量 | 17kDa |
| 檢測(cè)分子量 | 20 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | Human |
| 序 列 | 26-177/177 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達(dá)系統(tǒng) | E.coli |
| 活性 | Not tested |
| 標(biāo)簽 | His |
| 緩 沖 液 | PBS (pH=7.4) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. SWISS: P18510 Gene ID: 3557 ????L-lra-重組人白介素-1受體拮抗劑，通過(guò)與白細(xì)胞介素-1的Ⅰ型和Ⅱ型受體結(jié)合，特異性地阻斷白細(xì)胞介素-1的生物學(xué)作用。白介素1受體拮抗劑(IL-1Ra)是體內(nèi)天然的一種對(duì)IL-1有拮抗作用的細(xì)胞因子。國(guó)際上對(duì)其的研究愈來(lái)愈受到重視。 重組人白介素1受體拮抗劑(rhIL-1Ra)作為一種生物制劑已經(jīng)FDA批準(zhǔn)應(yīng)用于臨床治療細(xì)胞因子。 ????重組白介素1受體拮抗劑，分子量約17kD，純度大于98%。 |
| 產(chǎn)品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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