產(chǎn)品編號 | bs-0391P |
英文名稱 | Recombinant human CRP protein, C-His |
中文名稱 | 重組人C反應蛋白 |
別 名 | C-reactive protein; C Reactive Protein; C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C-reactive protein(1-205); CRP_HUMAN; Pentraxin 1; Human C Reactive Protein full length protein; Recombinant human CRP protein, C-His |
Specific References (1) | bs-0391P has been referenced in 1 publications. [IF=4.916] Rong Z et al. A C-reactive protein immunosensor based on platinum nanowire/titania nanotube composite sensitized electrochemiluminescence. Talanta, 2019.205, 120135. Other ; | |
理論分子量 | 23kDa |
檢測分子量 | 25 kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 19-224/224 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達系統(tǒng) | E.coli |
活性 | Yes |
標簽 | C-His |
緩 沖 液 | 10 mM TBS (pH=7.4) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture. SWISS: P02741 Gene ID: 1401 |
產(chǎn)品圖片 | |
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