產(chǎn)品編號 | bs-10820P |
英文名稱 | Recombinant human CD34 protein, C-His |
中文名稱 | 重組人CD34蛋白 |
別 名 | CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN; Recombinant human CD34 protein, C-His |
理論分子量 | 28.6kDa |
檢測分子量 | 35 kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 32-290/385 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達系統(tǒng) | E.coli |
活性 | Not tested |
標簽 | C-His |
緩 沖 液 | PBS (pH=7.4) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence. SWISS: P28906 Gene ID: 947 |
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