產品編號 | bs-41083P |
英文名稱 | Recombinant human PEDF protein, His |
中文名稱 | 重組人色素上皮源性因子蛋白 |
別 名 | pigment epithelium-derived factor; Serpin-F1; Stromal cell-derived factor 3; SDF-3; Caspin; Alpha 2 antiplasmin; EPC 1; EPC1; PIG 35; PIG35; Pigment epithelium derived factor; Proliferation inducing protein 35; SERPIN F1; Serpin peptidase inhibitor clade F member 1; SERPINF 1; SERPINF1; PEDF_HUMAN; Recombinant human PEDF protein, His |
理論分子量 | 45.2kDa |
檢測分子量 | 55 kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 20-418/418 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內毒素 | Not analyzed |
表達系統(tǒng) | E.coli |
活性 | Not tested |
標簽 | His |
緩 沖 液 | 20 mM Tris-HCl (pH=8.0) with 8 M Urea |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產品介紹 | Pigment epithelium derived factor, originally identified in conditioned medium of cultured human fetal retinal pigment epithelial (RPE) cells, is a neurotrophic protein that induces extensive neuronal differentiation in human Y79 retinoblastoma cells, a neoplastic counterpart of normal retinoblasts. It has been suggested that PEDF is synthesized by RPE cells and secreted into the retina interphotoreceptor matrix where it may influence development/differentiation of the neural retina. PEDF is a potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity. SWISS: P97298 Gene ID: 5176 |
產品圖片 | |
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