產(chǎn)品編號 | bs-41190P |
英文名稱 | Recombinant Streptolysin O protein, His |
中文名稱 | 重組鏈球菌溶血素O |
別 名 | SLO; Thiol-activated cytolysin; SPs0132; Recombinant Streptolysin O protein, His |
理論分子量 | 56kDa |
檢測分子量 | 62 kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Streptococcus |
序 列 | 78-571/571 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達(dá)系統(tǒng) | E.coli |
活性 | Not tested |
標(biāo)簽 | His |
緩 沖 液 | 20 mM Tris-HCl (pH=8.0) with 150 mM NaCl. |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Streptolysin is a streptococcal hemolytic exotoxin. Types include streptolysin O (SLO), which is oxygen-labile, and streptolysin S (SLS), which is oxygen-stable. An antibody, antistreptolysin O, can be detected in an antistreptolysin O titre. Streptolysin O is hemolytically active only in a reversibly reduced state, unlike streptolysin S, which is stable in the presence of oxygen. Another difference is that SLO is antigenic, while SLS is not antigenic due to its small size. The main function of streptolysin O is to cause hemolysis (the breaking open of red blood cells) — in particular, beta-hemolysis. Increased levels of aso titre in the blood could cause damage to the heart and joints. In most cases, penicillin is used to treat patients with increased levels of aso titre. SWISS: P0DF97 Gene ID: 57851997 |
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