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重組人生長刺激表達基因2蛋白

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產(chǎn)品編號bs-41103P
英文名稱Recombinant human ST2 protein, His
中文名稱重組人生長刺激表達基因2蛋白
別    名DER-4; DER4; FIT 1; Growth stimulation expressed gene 2; homolog of mouse growth stimulation-expressed; Il1rl1; IL33R; ILRL1_HUMAN; Interleukin 1 receptor like 1; interleukin 1 receptor related protein; Interleukin-1 receptor-like 1; Ly84; Lymphocyte antigen 84; Protein ST2; ST2; ST2L; ST2V; Ste2; Suppressor of tumorigenicity 2; T1; T1 protein; Recombinant human ST2 protein, His  
理論分子量36kDa
檢測分子量40 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Human
序    列19-328/556
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達系統(tǒng)E.coli
活性Yes
標簽His
緩 沖 液20 mM Tris-HCl (pH=7.2) with 1 M Urea
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.

SWISS:
Q01638

Gene ID:
9173

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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