產(chǎn)品編號(hào) | bs-41373P |
英文名稱 | Recombinant mouse GAPDH protein, His |
中文名稱 | 重組小鼠3-磷酸甘油醛脫氫酶蛋白 |
別 名 | Glyceraldehyde-3-phosphate dehydrogenase; Recombinant mouse GAPDH protein, His |
理論分子量 | 35.8kDa |
檢測(cè)分子量 | 38 kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Mouse |
序 列 | 1-333/333 |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達(dá)系統(tǒng) | E.coli |
活性 | Not tested |
標(biāo)簽 | His |
緩 沖 液 | 20 mM Tris-HCl (pH=8.0) with 200 mM Arg |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, thereversible oxidative phosphorylation of glyceraldehyde-3-phosphatein the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots. |
產(chǎn)品圖片 | |
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