| 產(chǎn)品編號(hào) | bs-41362P |
| 英文名稱 | Recombinant human SGK3 protein |
| 中文名稱 | 重組人絲氨酸蛋白激酶Sgk3蛋白 |
| 別 名 | CISK; Cytokine independent survival kinase; Serine/threonine protein kinase Sgk3; Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid regulated kinase 3; Serum/glucocorticoid regulated kinase family member 3; Serum/glucocorticoid regulated kinase like; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like; SGK 2; SGK 3; SGK2; Sgk3; SGK3_HUMAN; SGKL. |
| 理論分子量 | 44.8kDa |
| 檢測(cè)分子量 | 42 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >0.5 mg/ml |
| 序 列 | 160-496/496 |
| 純 度 | >90% by SDSD-PAGE |
| 內(nèi)毒素 | Not analyzed |
| 活性 | No tested |
| 標(biāo)簽 | N-His Tag |
| 緩 沖 液 | PBS pH7.5 |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Serine/threonine-protein kinase Sgk3 (SGK3), also designated serum/glucocorticoid regulated kinase 3, belongs to the Ser/Thr protein kinase family of proteins. The serum- and glucocorticoid-regulated kinase proteins are closely related to the Akt protein family. SGK1, a homolog of SGK3, activates ion channels, in particular potassium (K+) channels. SGK2 and SGK3 have been found to also be involved in this activation process, making all three of these proteins important regulators for cell proliferation, epithelial transport and neuromuscular excitability. SGK3 acts as a mediator of IL-3 dependent survival signals in the cell. It localizes to the early endosome and in vesicle-like structures. SGK3 is a widely expressed protein, but it is primarily detected in kidney, liver, pancreas, brain and heart. Phosphorylation of SGK3 at residue Ser 486 leads to an increase in SGK3 activation. SWISS: Q96BR1 Gene ID: 100533105 |
| 產(chǎn)品圖片 |  The purity of the protein is greater than 24% as determined by reducing SDS-PAGE. |
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