產(chǎn)品編號(hào) | bs-43532P |
英文名稱 | Recombinant mouse CD160 protein, C-His Tag (HEK293) |
中文名稱 | 重組小鼠CD160蛋白 |
別 名 | By55; Natural killer cell receptor BY55; BY55; CD160 antigen [Precursor]; CD160 molecule; FLJ46513; Natural killer cell receptor BY55; NK1; NK28; BY55_HUMAN; Recombinant mouse CD160 protein, C-His Tag (HEK293) |
理論分子量 | 19.9kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Mouse |
序 列 | 28-160/185 |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達(dá)系統(tǒng) | HEK293 cell |
活性 | Not tested |
標(biāo)簽 | C-His Tag |
緩 沖 液 | PBS (pH=7.4) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] SWISS: O95971 Gene ID: 11126 |
產(chǎn)品圖片 | |
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