產(chǎn)品編號 | bs-43146P |
英文名稱 | Recombinant human Renin protein, C-His (HEK293) |
中文名稱 | 重組人腎素/血管緊張素形成酶Ren1蛋白 |
別 名 | Angiotensin forming enzyme; Angiotensin forming enzyme precursor; Angiotensinogenase; Angiotensinogenase precursor; HNFJ2; REN; Renin1; Renin-1; Renin 1; Ren1; RENI_HUMAN; Renin; Renin precursor renal. |
理論分子量 | 44.4kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >1mg/ml |
物 種 | Human |
序 列 | 24-406/406 |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達系統(tǒng) | HEK293 cell |
活性 | Not tested |
標簽 | C-His |
緩 沖 液 | PBS (pH=7.4) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]. SWISS: P00797 Gene ID: 5972 |
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