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葡萄糖調(diào)節(jié)蛋白94封閉多肽

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產(chǎn)品編號bs-0194P
英文名稱HSP90B1 Antibody Blocking Peptide
中文名稱葡萄糖調(diào)節(jié)蛋白94封閉多肽
別    名HSP gp96; heat shock protein gp96 precursor; 94 kDa glucose regulated protein; ECGP; Endoplasmin; Endothelial cell (HBMEC) glycoprotein; Glucose regulated protein 94; Glucose regulated protein 94kDa; gp96; gp96 homolog; GRP 94; Heat shock protein 90 kDa beta member 1; HSP90B1; Stress inducible tumor rejection antigen GP96; TRA1; Tumor rejection antigen 1; Tumor rejection antigen gp96; ENPL_HUMAN; Endoplasmin.  
性    狀Lyophilized powder
物    種human
純化方法HPLC
活性Not tested
保存條件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹bs-0194P is one synthetic peptide derived from human GRP94.
Glucose regulated protein 94 (GRP 94) is a resident protein of the endoplasmic reticulum (ER) and is induced by the accumulation of unfolded proteins suggesting that it might associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C terminus of GRP 94 and other resident ER proteins including GRP 78 and protein disulfide isomerase (PDI). The presence of carboxy terminal KDEL appears to be necessary for retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor. GRP 94 is also a low affinity, high capacity calcium binding protein, though it's role, if any, in calcium regulation is not understood.

SWISS:
P14625

Gene ID:
7184

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