產(chǎn)品編號(hào) | bs-0030P |
英文名稱 | PPP3CA Antibody Blocking Peptide |
中文名稱 | 鈣調(diào)磷酸酶A/鈣依賴磷酸酶A封閉多肽 |
別 名 | Calcineurin A alpha; CalcineurinA; Calcineurin-A; Calcineurin A; Calmodulin dependent calcineurin A subunit alpha isoform; CALN; CALNA 1; CALNA; CALNA1; CAM PRP catalytic subunit; CCN 1; CCN1; CNA 1; CNA; CNA1; PPP2B; Protein phosphatase 3 (formerly 2B) catalytic subunit alpha isoform; Serine/threonine protein phosphatase 2B catalytic subunit alpha isoform; PP2BA_HUMAN; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform; protein phosphatase 2B, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform. |
性 狀 | Lyophilized powder |
物 種 | human |
純化方法 | HPLC |
活性 | Not tested |
保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 | Calcineurin, a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. This metalloenzyme, also known as phosphatase 2B, is a heterodimer composed of a calmodulin binding, catalytic alpha subunit 61 kDa, calcineurin A) and calcium binding beta subunit (18 kDa, calcineurin B). The Ca2+ binding subunit, calcineurin B, is immunologically conserved from yeast to mammals. The presence of 2 different calcineurin B isoforms (beta 1 and beta 2) has been reported in rat testis. The catalytic subunit of calcineurin, calcineurin A, isolated from different tissues or different organisms, exhibits some immunological heterogeneity. Further, there are at least 2 isoforms of calcineurin A in bovine brain (alpha 1 and alpha 2, 61 and 59 kDa, respectively). SWISS: Q08209 Gene ID: 5530 |
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