| 產(chǎn)品編號 | bs-0990P |
| 英文名稱 | HPV16 E6 Antibody Blocking Peptide |
| 中文名稱 | 人類乳頭狀瘤病毒16封閉多肽 |
| 別 名 | E6; Human Papilloma Virus; Human papillomavirus type 16 E6; Human papillomavirus type 16; Protein E6; E6 protein; HPV16 E6; HPV16-E6; VE6_HPV16. |
 | Specific References (2) | bs-0990P has been referenced in 2 publications. [IF=9.518] Chen Y et al. A multiple mixed TiO2 mesocrystal junction based PEC-colorimetric immunoassay for specific recognition of lipolysis stimulated lipoprotein receptor. Biosens Bioelectron. 2019 Oct 26;148:111809. Other ; [IF=7.46] Yanjie Chen. et al. A portable multi-signal readout sensing platform based on plasmonic MXene induced signal amplification for point of care biomarker detection. Sensor Actuat B-Chem. 2022 Feb;352:131059 |
| 性 狀 | Lyophilized powder |
| 物 種 | HPV16 |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 | Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa. Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae. However, some subtypes, notably types 16 and 18, 31 and 33, have been confirmed as agents which cause cervical cancer. SWISS: P03126 Gene ID: 1489078 |
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