產(chǎn)品編號 | bs-0486P |
英文名稱 | ITGB1 Antibody Blocking Peptide |
中文名稱 | 整合素β1/Integrin β1封閉多肽 |
別 名 | Integrin beta 1; Integrin beta-1; beta 1 subunit; CD 29; CD-29; CD29; CD29 antigen; Fibrinogen Receptor beta subunit; Fibronectin receptor subunit beta; Fibronectin receptor, beta subunit; FNRB; GPIIA; integrin beta 1 (fibronectin receptor beta polypeptide antigen CD29 includes MDF2 MSK12); Integrin VLA 4 subunit beta; ITGB; ITGB1; MDF2; MSK12; Very Late Activation Protein beta Polypeptide; VLAB; VLAbeta; Glycoprotein IIa; GP IIa; Integrin VLA 4 subunit beta; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITB1_HUMAN; ITGB 1; ITGB1; OTTHUMP00000019420; Very Late Activation Protein beta Polypeptide; very late activation protein, beta polypeptide; VLA BETA; VLA-4 subunit beta; VLA-BETA; VLAB; VLAbeta. Integrin beta-1; beta 1 subunit; CD 29; CD-29; CD29 antigen; Fibrinogen Receptor beta subunit; Fibronectin receptor subunit beta; Fibronectin receptor, beta subunit; integrin beta 1 (fibronectin receptor beta polypeptide antigen CD29 includes MDF2 MSK12); Integrin VLA 4 subunit beta; Very Late Activation Protein beta Polypeptide; Glycoprotein IIa; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); OTTHUMP00000019420; Very Late Activation Protein beta Polypeptide; very late activation protein, beta polypeptide; |
性 狀 | Lyophilized powder |
物 種 | human |
純化方法 | 1 |
活性 | Not tested |
保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 | Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. SWISS: P05556 Gene ID: 3688 |
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