| 產(chǎn)品編號(hào) | bs-0791P |
| 英文名稱 | CALCA Antibody Blocking Peptide |
| 中文名稱 | 降鈣素基因相關(guān)肽1/2封閉多肽 |
| 別 名 | CGRP-I + CGRP-II; CGRP-1/2; Procalcitonin; Beta type CGRP; CALC2; CALCB; Calcitonin 1; Calcitonin 2; Calcitonin gene related peptide; Calcitonin gene related peptide II; Calcitonin related polypeptide beta; CGRP; CGRP II; CGRP2; CT; Calcitonin/calcitonin related polypeptide alpha; Katacalcin; MGC126648; CALCA_HUMAN; CALCB_HUMAN; Calcitonin gene-related peptide 2; Beta-type CGRP; Beta-CGRP; Calcitonin gene-related peptide II; CGRP-II; CGRP-I. |
 | Specific References (1) | bs-0791P has been referenced in 1 publications. [IF=3.877] Zhang et al. Effects of Neuropeptide Substance P on Proliferation and β-Cell Differentiation of Adult Pancreatic Ductal Cells. (2018) Front.Neurosci. 12:806 |
| 性 狀 | Lyophilized powder |
| 物 種 | mouse |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 | CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed. SWISS: P06881/P10092 Gene ID: 796/797 CGRP活性多肽，有37個(gè)氨基酸組成，具有多種生理功能，其藥理作用已受到廣泛重視. CGRP （又稱CGRP-1/2或CGRPa/β）廣泛分布于神經(jīng)系統(tǒng)的一種神經(jīng)肽，在外周及脊髓參與傷害性信息的傳遞及痛敏化的形成，并與P物質(zhì)、興奮性氨基酸、辣椒素1型受體、趨化因子、激活素、大麻素受體、阿片受體、神經(jīng)生長(zhǎng)因子、血管活性腸肽、5-羥色胺、糖皮質(zhì)激素等生物活性物質(zhì)或受體在痛覺(jué)調(diào)制過(guò)程中存在相互影響。 |
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