| 產(chǎn)品編號 | bs-0749P |
| 英文名稱 | Kiss-1 Antibody Blocking Peptide |
| 中文名稱 | 腫瘤轉(zhuǎn)移抑制基因封閉多肽 |
| 別 名 | KiSS-1 Metastasis Suppressor; Prepro-Kisspeptin; Kisspeptin-1; Malignant Melanoma Metastasis-Suppressor; Metastasis-Suppressor KiSS-1; Kisspeptin; Metastin; KiSS-1; HH13; KISS1_HUMAN; |
| 性 狀 | Lyophilized powder |
| 物 種 | human |
| 純化方法 | 1 |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 | This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012] SWISS: Q15726 Gene ID: 3814 Kiss-1主要用于腫瘤及腫瘤轉(zhuǎn)移方面的研究。 |
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