| 產(chǎn)品編號 | bs-2373P |
| 英文名稱 | CP Antibody Blocking Peptide |
| 中文名稱 | 銅藍蛋白封閉多肽 |
| 別 名 | CER; caeruloplasmin; Ceruloplasmin precursor; CP 2; CP; CP2; CP-2; EC 1.16.3.1; Ferroxidase; CERU_HUMAN. |
| 性 狀 | Lyophilized powder |
| 物 種 | human |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Caeruloplasmin is a copper binding plasma glycoprotein consisting of a single polypeptide chain. It has a molecular weight of 132kDa and occurs in plasma at a concentration of 150-500 mg/L. Although the physiological functions of Caeruloplasmin are not fully understood it is implicated in a number of possible functions. 95% of plasma copper is bound to Caeruloplasmin, implying some involvement in copper transport. Caeruloplasmin has been described as both an oxidant and an antioxidant, its exact role or roles in this respect are not clear. Plasma levels of Caeruloplasmin are elevated after inflammation and trauma and it is therefore classified as an acute phase protein. The measurement of Caeruloplasmin in plasma is useful in the diagnosis of Wilson’s disease, where levels are greatly reduced. Caeruloplasmin is extremely labile in plasma and rapidly degrades to 115kDa and 19kDa fragments. The age of plasma samples should therefore be taken into account when interpreting immunological analysis of caeruloplasmin SWISS: P00450 Gene ID: 1356 銅藍蛋白（ceruloplasmin,CER）又稱銅氧化酶，是一種含銅的α2糖蛋白，CER具有氧化酶的活性，起著抗氧化劑的作用。在血循環(huán)中CER的抗氧化活力可以防止組織中脂質(zhì)過氧化物和自由基的生成，特別在炎癥時具有重要意義,也屬于一種急性時相反應蛋白。 銅藍蛋白對多酚及多胺類底物有催化其氧化之能力銅藍蛋白具有遺傳上的基因多形性。其作用為調(diào)節(jié)銅在機體各個部位的分布、合成含銅的酶蛋白.一般認為銅藍蛋白由肝臟合成，一部分由膽道排泄，尿中含量甚微。銅藍蛋白測定對某些肝、膽、腎等疾病的診斷有一定意義。 |
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