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組織因子途徑抑制劑封閉多肽

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產(chǎn)品編號(hào)bs-2535P
英文名稱TFPI Antibody Blocking Peptide
中文名稱組織因子途徑抑制劑封閉多肽
別    名Tissue factor pathway inhibitor-1; convertin; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein associated coagulation inhibitor; TFI; TFPI 1; TFPI1; Tissue factor pathway inhibitor; TFPI1_HUMAN.  
性    狀lyophilized powder
物    種human
內(nèi)毒素Not analyzed
活性Not tested
標(biāo)簽N/A
保存條件Stored at -20℃ for one year.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.

SWISS:
P10646

Gene ID:
7035

組織因子途徑抑制因子(tissue factor pathway in hibitor, TFPI)是組織因子凝血途徑的主要抑制因子, 組織因子途徑抑制因子在諸如動(dòng)脈粥樣硬化,血管再狹窄,彌漫性血管內(nèi)凝血DIC等方面,有一定的研究價(jià)值。
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