| 產(chǎn)品編號 | bs-5109P |
| 英文名稱 | HCLS1 Antibody Blocking Peptide |
| 中文名稱 | 造血干細胞特異性蛋白封閉多肽 |
| 別 名 | Cortactin like; CTTNL; HCLS 1; HCLS 1 protein; Hcls1; HCLS1 protein; HCLS1_HUMAN; Hematopoietic cell specific Lyn substrate 1; Hematopoietic cell-specific LYN substrate 1; Hematopoietic lineage cell specific protein; Hematopoietic lineage cell-specific protein; HS 1; HS1; LckBP 1; LckBP1; p75 antibody. |
| 性 狀 | Lyophilized powder |
| 物 種 | human |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. Subunit : Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to the LCK SH2 domain occurs only upon TCR stimulation. A similar binding pattern was observed with LYN, but not with FYN in which the FYN SH2 region associates upon TCR stimulation but the FYN SH3 region does not associate regardless of TCR stimulation. Directly associates with HAX1, through binding to its C-terminal region. Interacts with HS1BP3. Interacts with FES/FPS. Interacts (via SH2 domain) with FGR. Forms a multiprotein complex with LYN and ANKRD54. SWISS: P14317 Gene ID: 3059 |
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