| 產(chǎn)品編號 | bs-4535PB |
| 英文名稱 | DHT/BSA |
| 中文名稱 | 雙氫睪酮牛血清白蛋白偶聯(lián)物 |
| 別 名 | Dihydrotestosterone conjugated to BSA. |
| 理論分子量 | N/AkDa |
| 性 狀 | Liquid |
| 物 種 | N/A |
| 序 列 | Coupling protein |
| 內(nèi)毒素 | Not analyzed |
| 活性 | No |
| 標(biāo)簽 | N/A |
| 緩 沖 液 | 0.01M PBS(pH7.4) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Dihydrotestosterone is a biologically active metabolite of the hormone testosterone, formed primarily in the prostate gland, testes, hair follicles, and adrenal glands by the enzyme 5a-reductase by means of reducing the 4,5 double-bond. Dihydrotestosterone is produced by males in utero and is responsible for the formation of male gender-specific characteristics as well as contributing to other characteristics generally attributed to males, including facial and body hair growth, and deepening of the voice. 雙氫睪酮亦稱17β－羥基-5α-雄[甾]烷-3-酮、5α－二氫睪酮、5α－DHT、或雄烷酮（stanorone）。是睪酮的雙鍵在5α處被還原的甾醇。對附屬腺（前列腺、精囊腺等），起著所謂的真的雄性激素的作用。在附屬性腺的細(xì)胞中存在著形成該甾醇的5α-氫化酶。該甾醇和受體蛋白質(zhì)在細(xì)胞內(nèi)結(jié)合成的復(fù)合體進(jìn)入附屬腺的細(xì)胞核中，促進(jìn)新的蛋白質(zhì)合成。顯示出比睪酮稍強的雄性激素作用。5β-體雖在肝臟、雞冠等中以睪酮形態(tài)存在，但是沒有雄性激素的作用。5α－二氫睪酮由于3α-羥基甾醇脫氫酶的作用而代謝成為5α-雄烷-3α－17β-二醇排出體外。 |
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