| 產(chǎn)品編號 | bs-4561P |
| 英文名稱 | Bivalirudin Antibody Blocking Peptide |
| 中文名稱 | 比伐盧定（水蛭素類似物）封閉多肽 |
| 別 名 | Bivalirudin; 128270-60-0 Hirudin |
| 理論分子量 | 2.108kDa |
| 性 狀 | Lyophilized powder |
| 物 種 | human |
| 序 列 | d-FPRPGGGGNGDFEEIPEEYL |
| 純化方法 | HPLC |
| 活性 | Yes |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI). Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis). Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore, it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin. SWISS: N/A Gene ID: 128270-60-0 CAS NO：128270-60-0 SEQUENCE：FPRPGGGGNGDFEEIPEEYL MODIFICATION：D-Phe(1) MOLECULAR WEIGHT：2108.3 MOLECULAR FORMULA：C98H138N24O33 COMPOUND ID(CID)：16129704 |
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