產(chǎn)品編號 | bs-4989P |
英文名稱 | BDNF Antibody Blocking Peptide |
中文名稱 | 腦源神經(jīng)營養(yǎng)因子封閉多肽 |
別 名 | Abrineurin; BDNF; BDNF; BDNF_HUMAN; Brain Derived Neurotrophic Factor; Brain-derived neurotrophic factor; MGC34632; MGC34632; Neurotrophin. |
Specific References (1) | bs-4989P has been referenced in 1 publications. [IF=1.98] Xu HY et al. Protective Effect of Mesenchymal Stromal Cell-Derived Exosomes on Traumatic Brain Injury via miR-216a-5p. Med Sci Monit. 2020; 26: e920855-1–e920855-12. other ; rat. | |
性 狀 | Lyophilized powder |
物 種 | human |
純化方法 | 1 |
活性 | Not tested |
保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. More recently, three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4), also designated NT-5. These various neurotrophins stimulate the in vitro survival of distinct but partially overlapping populations of neurons. The Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds equally well to both BDNF and NT-4 and to a lesser extent NT-3, while the Trk C receptor only binds NT-3. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Belongs to the NGF-beta family. SWISS: P23560 Gene ID: 627 |
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