| 產(chǎn)品編號(hào) | bs-11129P |
| 英文名稱 | CNTNAP2 Antibody Blocking Peptide |
| 中文名稱 | 軸突相關(guān)CNTP2蛋白/少突膠質(zhì)細(xì)胞封閉多肽 |
| 別 名 | Cell recognition molecule Caspr2; Cntnap2; CNTP2; CNTP2_HUMAN; Contactin-associated protein-like 2. |
| 性 狀 | Lyophilized powder |
| 物 種 | human |
| 純化方法 | HPLC |
| 活性 | Not tested |
| 保存條件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | bs-11129P is one synthetic peptide derived from human Caspr2. CASPR is a transmembrane glycoprotein of the neurexin superfamily that is highly enriched in regions of myelinated axons. The axons of myelinated nerves in the adult nervous system possess specialized subcellular structures essential for efficient and rapid action potential propagation. CASPR and the closely related molecule CASPR2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. While CASPR is present at the paranodal junctions, CASPR2 is precisely colocalized with Shaker-like K+ channels in the juxtaparanodal region. CASPR2 specifically associates with Kv1.1, Kv1.2, and their Kvbeta2 subunit. CASPR family members may play a role in the local differentiation of the axon into distinct functional subdomains. SWISS: Q9UHC6 Gene ID: 26047 |
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