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重組人微管相關(guān)蛋白

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產(chǎn)品編號bs-46540P
英文名稱Recombinant human Tau-F protein
中文名稱重組人微管相關(guān)蛋白
別    名Recombinant human Tau-F protein  
理論分子量48.51kDa
檢測分子量65 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Human
序    列1-441/758
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
活性Not tested
標(biāo)簽Tag free
緩 沖 液Supplied as solution form in PBS (pH=7.4) or lyophilized from PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

SWISS:
P10636

Gene ID:
4137

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