產(chǎn)品編號 | bs-47087P |
英文名稱 | Recombinant human Fas Ligand protein, N-His (HEK293) |
中文名稱 | 重組人Fas Ligand(CD178)蛋白 |
別 名 | Tumor necrosis factor ligand superfamily member 6; FASLG; APO1L; Apoptosis (APO 1) antigen ligand 1; Fas-L; Apoptosis antigen ligand 1; APTL; CD178; CD-178; CD 178; CD95L; CD95 ligand; CD95-L; CD95L protein; FAS antigen ligand; Fas L; FASL; Fas ligand (TNF superfamily member 6); Generalized lymphoproliferative disease; TNF superfamily member 6; TNFSF6; TNFL6_HUMAN; Apoptosis antigen ligand; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; FASLG; Recombinant human Fas Ligand protein, N-His (HEK293) |
理論分子量 | 35kDa |
檢測分子量 | Due to glycosylation, the protein migrates to 20-35 kDa based on Tris-Bis PAGE result. |
性 狀 | Lyophilized powder |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 134-281/281 |
純 度 | >95% as determined by Tris-Bis PAGE |
純化方法 | AC |
內(nèi)毒素 | <1.0 EU/μg as determined by LAL |
表達系統(tǒng) | HEK293 cell |
活性 | Not tested |
標(biāo)簽 | N-His |
緩 沖 液 | Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] SWISS: AAH17502 Gene ID: 356 |
產(chǎn)品圖片 | |
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