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重組小鼠CD36蛋白

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產(chǎn)品編號(hào)bs-42054P
英文名稱(chēng)Recombinant mouse CD36 protein, C-His
中文名稱(chēng)重組小鼠CD36蛋白
別    名Platelet glycoprotein 4; PAS-4; Platelet glycoprotein IV; Glycoprotein IIIb; GPIV; GPIIIB; GP3B; Leukocyte differentiation antigen CD36; PAS IV; Platelet collagen receptor; Fatty acid translocase; FAT; Thrombospondin receptor; CD_antigen: GP4; CD36_MOUSE.  
理論分子量47.6kDa
性    狀Lyophilized or Liquid
濃    度>0.5mg/ml
物    種Mouse
序    列30-439/472
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
標(biāo)簽C-His
緩 沖 液20mM Tris-Hcl (pH=8.0) with 8M Urea and 0.3M L-Arg
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

SWISS:
Q08857

Gene ID:
12491

CD36屬一種多功能細(xì)胞膜受體,CD36參與長(zhǎng)鏈脂肪酸的吸附和調(diào)節(jié)細(xì)胞凋亡殘物的清理和巨噬細(xì)胞的吞噬作用, 屬于一種抗蛋白酶血小板膜表面糖蛋白。
CD36 廣泛在單核細(xì)胞、巨噬細(xì)胞、內(nèi)皮層細(xì)胞、血小板、紅細(xì)胞前板、脂肪細(xì)胞、肌肉細(xì)胞以及乳腺內(nèi)皮層細(xì)胞中有不同的表達(dá)。CD36抗原是血小板反應(yīng)素的配體,兩者結(jié)合后產(chǎn)生抑制腫瘤血管生成的效應(yīng)。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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