產(chǎn)品編號 | bs-42276P |
英文名稱 | Recombinant human CK17 protein, N-Trx-His |
中文名稱 | 人細胞角蛋白17重組蛋白 |
理論分子量 | 66.1kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >1mg/ml |
物 種 | Human |
序 列 | 1-432/432 |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達系統(tǒng) | E.coli |
標簽 | N-Trx-His |
緩 沖 液 | 20mM Tris-Hcl (pH=8.0) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]. SWISS: Q04695 Gene ID: 3872 結構蛋白(Structural Proteins) 常用于腫瘤細胞的分化、增殖及轉移方面的研究。 |
產(chǎn)品圖片 | |
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