Product Details
- Verified Reactivity
- SARS-CoV-2
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial recombinant SARS-CoV-2 S protein corresponding to S2 subunit
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
Direct ELISA - Verified - Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.1?- 1.0??g/mL. ?For the Direct ELISA application, a concentration of 3.7?ng/mL is recommended.?It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2888742 (BioLegend Cat. No. 943201) AB_2888742 (BioLegend Cat. No. 943202)
Antigen Details
- Structure
- Spike glycoprotein is a homotrimer. Each monomer consists of 1,273 amino acids with a theoretical molecular weight of 141 kD, and consists of S1 and S2 subunits. The S2 domain is 587 amino acids long with a predicted molecular weight of 64 kD.
- Distribution
-
Viral envelope protein, host cell membrane, host cell endoplasmic reticulum-Golgi intermediate compartment membrane
- Function
- Mediates fusion between virus and host cell membranes
- Interaction
- ACE2
- Ligand/Receptor
- ACE2
- Biology Area
- COVID-19
- Antigen References
- 1. Walls AC, et al. 2020. Cell. 181(2):281-292.2. Yan R, et al. 2020. Science. 367 (6485):1444-1448.3. Wrapp D, et al. 2020. Science. 367 (6483):1260-1263.4. Shang J, et al. 2020. PNAS. 117(21):11727-11734
- Gene ID
- 43740568 View all products for this Gene ID
- UniProt
- View information about Viral Protein on UniProt.org
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