Product Details
- Verified Reactivity
- SARS-CoV-2
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- SARS-CoV-2
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
Block - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by blocking the binding of 0.5 ?g/mL recombinant human ACE2 (Cat. No. 792002) to 1 ?g/mL immobilized recombinant SARS-CoV-2 S protein RBD-Fc chimera (Cat. No. 793104). ND50 range: 0.05 - 0.25 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2892509 (BioLegend Cat. No. 944803) AB_2892509 (BioLegend Cat. No. 944804)
Antigen Details
- Structure
- Disulfide linked homodimer
- Distribution
-
SARS-CoV-2
- Function
- Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection
- Interaction
- Lung cells
- Ligand/Receptor
- ACE2
- Biology Area
- COVID-19
- Antigen References
-
1. Lu R, et al. 2020. Lancet. 395:565-574.
2. Li F. 2016. Annu Rev Virol. 29:237-261.
3. Belouzard S, et al. 2012. Viruses. 4:1011-33.
4. Song W, et al. 2018. PLoS Pathog. 14(8).
5. Li F, et al. 2020. Nature. 581:221-224. - Gene ID
- NA
- UniProt
- View information about Viral Protein on UniProt.org
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